Watery Diarrhea Syndrome

Pancreatic polypeptide hyperplasia causing watery diarrhea syndrome: a case report.

Neuroendocrine tumours of the pancreas can secrete numerous peptides, leading to various recognizable clinical syndromes. The secretion of pancreatic polypeptide has been used as a marker for neuroendocrine tumours but is considered to be a biologically inert peptide. A 37-year-old woman had watery diarrhea syndrome from pancreatic polypeptide hyperplasia. Only 2 other reported cases in the lit...

Severe, Acute Watery Diarrhea in an Adult

1 Clinial Sciences Division, International Centre for Diarrhoeal Disease, Research, Bangladesh (ICDDR,B), Dhaka, Bangladesh, 2 Division of Infectious Diseases, Massachusetts General Hospital, Boston, Massachusetts, United States of America, 3 Department of Medicine, Harvard Medical School, Boston, Massachusetts, United States of America, 4 Department of Immunology and Infectious Diseases, Harva...

A 32-year-old man with copious, watery diarrhea.

Oral diosmectite reduces stool output and diarrhea duration in children with acute watery diarrhea.

BACKGROUND & AIMS Diosmectite is a clay used to treat children with acute watery diarrhea. However, its effects on stool output reduction, the key outcome for pediatric antidiarrheal drugs, have not been shown. METHODS Two parallel, double-blind studies of diosmectite efficacy on stool reduction were conducted in children 1 to 36 months old in Peru (n = 300) and Malaysia (n = 302). Inclusion ...

VIPomas and the watery diarrhoea syndrome.

Vaso-active intestinal polypeptide (VIP) is a recently discovered polypeptide widely distributed throughout the gastro-intestinal tract and nervous system. Elevated plasma VIP levels are found in gut and neural endocrine tumours producing the watery diarrhoea syndrome. Fifty per cent of these tumours are intrinsically malignant and the mortality rate may be as high as 30% even from the bening g...